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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
26.67
Human Site:
S309
Identified Species:
41.9
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S309
K
F
L
K
R
N
P
S
Q
R
I
G
G
G
P
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S309
K
F
L
K
R
N
P
S
Q
R
I
G
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
S336
K
F
L
K
R
N
P
S
Q
R
I
G
G
G
P
Dog
Lupus familis
XP_851971
482
53401
S307
K
F
L
K
R
N
P
S
Q
R
I
G
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
T309
K
F
L
K
R
N
P
T
Q
R
I
G
G
G
L
Rat
Rattus norvegicus
P67999
525
59113
A333
K
L
L
K
R
N
A
A
S
R
L
G
A
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
A290
K
L
L
K
R
N
A
A
S
R
L
G
A
G
P
Chicken
Gallus gallus
P18652
752
84421
A320
A
L
F
K
R
N
P
A
N
R
L
G
S
G
P
Frog
Xenopus laevis
P10665
733
82620
T302
A
L
F
K
R
N
P
T
N
R
L
G
S
A
M
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S307
M
L
F
K
R
N
P
S
N
R
L
G
A
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
K511
K
M
L
E
K
N
P
K
R
R
L
G
G
N
H
Honey Bee
Apis mellifera
XP_395876
456
51514
A311
K
L
L
K
R
Q
V
A
Q
R
L
G
S
G
P
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
Q344
A
L
F
K
R
N
S
Q
N
R
L
G
A
G
P
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
S314
K
L
L
K
R
H
I
S
A
R
L
G
S
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
V309
E
Y
M
A
P
E
I
V
R
G
K
G
H
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
100
100
N.A.
86.6
60
N.A.
60
53.3
40
60
N.A.
46.6
60
46.6
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
73.3
N.A.
73.3
66.6
53.3
66.6
N.A.
73.3
73.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
7
0
0
14
27
7
0
0
0
27
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
7
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
34
27
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
100
40
80
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
0
0
0
0
0
14
0
0
0
34
0
0
0
0
% I
% Lys:
67
0
0
87
7
0
0
7
0
0
7
0
0
0
7
% K
% Leu:
0
54
67
0
0
0
0
0
0
0
60
0
0
0
7
% L
% Met:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
80
0
0
27
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
7
0
60
0
0
0
0
0
0
0
74
% P
% Gln:
0
0
0
0
0
7
0
7
40
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
87
0
0
0
14
94
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
40
14
0
0
0
27
0
0
% S
% Thr:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _